There's plenty of male/male duos everywhere in gaming. Hell, most of the other Duo 3D Platforming series star two dudes. Those being Jack & Daxter and Ratchet & Clank. Can you name a single Female/Female 3D Platforming duo? It's unheard of! Games don't exist in vacuums. A game with a female duo would help balance the scales and thus be a super fair and progressive while the opposite would be less progressive than a game from 17 years ago. Not only would it be less progressive, but it'd be an entirely underwhelming reveal.
Status Quo is okay. Worked then, work now. I don't know if that's really exciting enough to hold for a reveal though. I feel like the only thing big enough for a reveal would be female duo. I can see them pitching "Hey we switched their genders!" as the thing but I think that's not really enough since we've been guessing Yooka would be female and Laylee would be male for months. Even that's not really out of left field.