They've already said they have some "different" ideas.
I'd like to see a bit of hybrid. Pure 2D seems a littlr over-traditional and Retro has already done that so well ... but I personally find that DK64s sections haven't aged the best.
My main expectstion is just that it should somehow feel like Yooka-Laylee, not a DK reskin
Given that he has sentience, this mine cart could presumably roll around off tracks sometimes, as well.