Splatoon: looks to be a breath of fresh air for a painfully stagnant genre. Loving the focus on territory control and team coordination.
Xenoblade Chronicles: played Xenoblade Chronicles on the Wii. One of the best rpgs of last gen, had some beautiful areas. This new entry looks like it could be even bigger than Skyrim, and with more interesting combat.
Yoshi's Woolly World: Overdose of cuteness. The art style looks incredible, and the game looks to have great platforming as well.
Zelda WiiU: Looks great so far. If Nintendo manages to combine the feeling of freedom and adventure in Wind Waker and Link Between Worlds with the storytelling of Majora's Mask, Zelda WiiU could be something really remarkable.